Myoclonic status secondary to cefepime toxicity by Camila Ramírez in Journal of Clinical Case Reports Medical Images and Health Sciences
Myoclonic status secondary to cefepime toxicity by Camila Ramírez in Journal of Clinical Case Reports Medical Images and Health Sciences Abstract Adverse drug reactions (ADRs) are defined as any harmful and unwanted effect that occurs at doses used for therapeutic or prophylactic purposes, being a frequent cause of mortality and morbidity. We present the case of a 36-year-old female patient with a history of HIV without antiretroviral therapy, in stage B2 (undetectable viral load, CD4 208) who was admitted due to emergency dialysis secondary to obstructive nephropathy due to ureterolithiasis. During hospitalization, she presented diarrheal episodes with isolation of Klebsiella pneumoniae in stool culture, which is why the treating service started therapy with cefepime not adjusted to renal function. Subsequently, she presented a sudden picture of altered state of consciousness, myoclonic and myoclonic status, for which extension studies were performed, with CT, electrolytes, gluc...