Numerous Ectopic Sebaceous Glands in the Esophagus; A Case Report and Assumption regarding Pathogenesis by Hideki Mori in Journal of Clinical Case Reports Medical Images and Health Sciences.
Numerous Ectopic Sebaceous Glands in the Esophagus A Case Report and Assumption regarding Pathogenesis by Hideki Mori in Journal of Clinical Case Reports Medical Images and Health Sciences. Abstract It is known that ectopic sebaceous glands (ESG) occur infrequently in the esophagus. ESG with numerous lesions of the esophagus are extremely rare. An endoscopic examination of a 79-year-old man revealed the presence of ESG more than 100 tiny lesions scattered throughout the esophagus. Immunohistochemically, keratin 14 (cytokeratin K14), ER (estrogen receptor) and Ki67 were predominantly expressed in the basal cells of ESG. Meanwhile, GATA3 (zinc finger transcription factor) was recognized mainly in the sebocytes of them. Clinicopathology of ESG and an assumption regarding pathogenesis of ESG, particularly in view of acquired metaplasia versus congenital misplacement is stated. Introduction Sebaceous gland is closely related to the hair follicle, forming the pilosebaceous ap...